circRNA basic information
circBase ID: -
Name: -
Synonym: circRNA-001175
Host Gene: -
Genomic location(hg19): -
Genomic location(hg38): -
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0007254
MONDO name: breast cancer
Disease details: breast cancer / BC
Disease DO ID:
 1612
Disease MeSH ID:
 -
Disease NCIt ID:
 C9335
Disease ICD11 ID:
 1047754165
Disease OMIM ID:
 -
Species: Human
Species details: Homo sapiens
Tissue specimen:

breast cancer tissue; paired adjacent non-cancerous tissue; tumor tissues; matched non-tumor tissues
Cell lines:

MCF-7; MDA-MB-231; MDA-MB-468; MDA-MB-453; SKBR-3; T47D; MCF-10A
In vivo animal model:

-
circRNA-disease information
Expression pattern:
UP
Associated gene: -
Associated microRNA: -
Biological function: circRNA-001175 was significantly upregulated in breast cancer tissues and maintained statistical significance in breast cancer cell lines, but its silencing had no significant effect on breast cancer cell viability and migration in preliminary results.
Molecular mechanism: -
Biological pathway or process:

not specified
Detected method:
Q
M
Validation methods:

RNase R Treatment; RT-qPCR; Microarray; Clinical Sample Validation
Clinical significance:

-
Description:

circRNA-001175 was identified by microarray and validated by RT-qPCR as an upregulated circRNA in breast cancer tissues. It also remained statistically significant in breast cancer cell lines, but the authors reported no significant effect of its silencing on cell viability and migration in preliminary experiments.
Confidence score:

0.4773
Other information
Title:

Comprehensive circular RNA profiling reveals the regulatory role of circRNA_0007694 in papillary thyroid carcinoma.

Journal: American journal of translational research
Published: 2020
PubMed ID: 32355548
Study type:

combined biological and clinical study
Data availability: GSE97332
Code availability: -