circRNA basic information
circBase ID: hsa_circ_0008039
Name: -
Synonym: -
Host Gene: -
Genomic location(hg19): chr7:716865-751164:-
Genomic location(hg38): chr7:677228-711527:-
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
0005575
MONDO name: colorectal cancer
Disease details: colorectal cancer / CRC
Disease DO ID:
5672, 9256
Disease MeSH ID:
-
Disease NCIt ID:
C4978
Disease ICD11 ID:
-
Disease OMIM ID:
114500
Species: Human
Species details: Homo sapiens
Tissue specimen:

tumour tissue; normal tissue; paracancer tissue

Cell lines:

-

In vivo animal model:

-

circRNA-disease information
Expression pattern:
DS
Associated gene: -
Associated microRNA: -
Biological function: staging biomarker potential
Molecular mechanism: -
Biological pathway or process:

not specified

Detected method:
S
Validation methods:

RNA-seq; Bioinformatics Analysis

Clinical significance:

Expression differs between early- and late-stage CRC, suggesting a staging biomarker.

Description:

hsa_circ_0008039 shows stage-associated expression changes in CRC (early vs late stage), indicating potential utility as a CRC staging biomarker.

Confidence score:

0.1768

Other information
Title:

Comprehensive circular RNA profiling provides insight into colorectal cancer pathogenesis and reveals diagnostically relevant biomarkers.

Journal: Clinical and translational medicine
Published: 2024
PubMed ID: 39397316
Study type:

combined biological and clinical study

Data availability: PRJCA019939; GSE161277; GSE221240; GSE235850
Code availability: https://github.com/wangjun‐bio/miRlab/tree/CRC