circRNA basic information
circBase ID: hsa_circ_0073244
Name: -
Synonym: -
Host Gene: -
Genomic location(hg19): chr5:83356118-83362425:-
Genomic location(hg38): chr5:84060299-84066606:-
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0005575
MONDO name: colorectal cancer
Disease details: colorectal cancer / CRC
Disease DO ID:
 5672, 9256
Disease MeSH ID:
 -
Disease NCIt ID:
 C4978
Disease ICD11 ID:
 -
Disease OMIM ID:
 114500
Species: Human
Species details: Homo sapiens
Tissue specimen:

tumour tissue; normal tissue; paracancer tissue
Cell lines:

-
In vivo animal model:

-
circRNA-disease information
Expression pattern:
UN
Associated gene: -
Associated microRNA: -
Biological function: diagnostic biomarker potential
Molecular mechanism: -
Biological pathway or process:

not specified
Detected method:
Q
S
Validation methods:

RNA-seq; Bioinformatics Analysis; ROC Analysis; RT-qPCR; Clinical Sample Validation; Back-Splice Junction PCR / divergent primers PCR; Sanger Sequencing
Clinical significance:

Outstanding diagnostic performance for CRC (AUC = 0.9717).
Description:

hsa_circ_0073244 was identified as a diagnostically relevant circRNA for CRC, showing outstanding discrimination between CRC and controls with AUC 0.9717 in the study's evaluation.
Confidence score:

0.6556
Other information
Title:

Comprehensive circular RNA profiling provides insight into colorectal cancer pathogenesis and reveals diagnostically relevant biomarkers.

Journal: Clinical and translational medicine
Published: 2024
PubMed ID: 39397316
Study type:

combined biological and clinical study
Data availability: PRJCA019939; GSE161277; GSE221240; GSE235850
Code availability: https://github.com/wangjun‐bio/miRlab/tree/CRC