circRNA basic information
circBase ID: hsa_circ_0005402
Name: hsa_circ_ANXA2
Synonym: hsa_circRNA_101539
Host Gene: ANXA2
Genomic location(hg19): chr15:60648117-60674640:-
Genomic location(hg38): chr15:60355918-60382441:-
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0004996
MONDO name: childhood acute myeloid leukemia
Disease details: Relapsed/refractory acute myeloid leukemia / R/R-AML
Disease DO ID:
 0070323
Disease MeSH ID:
 -
Disease NCIt ID:
 C9160
Disease ICD11 ID:
 -
Disease OMIM ID:
 -
Species: Human
Species details: Homo sapiens
Tissue specimen:

peripheral blood mononuclear cells (PBMCs)
Cell lines:

-
In vivo animal model:

-
circRNA-disease information
Expression pattern:
UP
Associated gene: -
Associated microRNA: -
Biological function: unknown
Molecular mechanism: circRNA/miRNA/mRNA network prediction (bioinformatics)
Biological pathway or process:

ceRNA regulation (other); Ras signaling (other)
Detected method:
M
Validation methods:

Microarray; Bioinformatics Analysis
Clinical significance:

-
Description:

This circRNA is among the upregulated candidate DE-circRNAs in R/R-AML versus de novo AML identified by circRNA microarray in PBMCs. The study only provides predicted circRNA/miRNA/mRNA network and pathway enrichment context, without direct mechanistic experiments for this circRNA.
Confidence score:

0.1768
Other information
Title:

Screening of a Prognostic Gene Signature for Relapsed/Refractory Acute Myeloid Leukemia Based on Altered Circulating CircRNA Profiles.

Journal: International journal of general medicine
Published: 2024
PubMed ID: 39006913
Study type:

combined biological and clinical study
Data availability: -
Code availability: -