circRNA basic information
circBase ID: hsa_circ_0060539
Name: hsa_circ_SDC4
Synonym: -
Host Gene: SDC4
Genomic location(hg19): chr20:43953928-43956055:-
Genomic location(hg38): chr20:45325288-45327415:-
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0008315
MONDO name: prostate cancer
Disease details: prostate cancer
Disease DO ID:
 10283
Disease MeSH ID:
 D011471
Disease NCIt ID:
 C7378
Disease ICD11 ID:
 -
Disease OMIM ID:
 -
Species: Human
Species details: Homo sapiens
Tissue specimen:

-
Cell lines:

22Rv1; LNCaP; VCaP; DU145; PC-3; BPH-1; PWR1; RWPE-1; PWR-1E; RWPE-1
In vivo animal model:

-
circRNA-disease information
Expression pattern:
UP
Associated gene: SDC4
Associated microRNA: -
Biological function: -
Molecular mechanism: Host-gene association with SDC4 identified via circBase/UCSC-based annotation; no functional mechanism experimentally validated.
Biological pathway or process:

not specified
Detected method:
M
Validation methods:

Microarray; Bioinformatics Analysis
Clinical significance:

-
Description:

hsa_circ_0060539 is highly up-regulated in malignant versus benign/normal prostate cell lines. It is bioinformatically linked to the host gene SDC4, but no downstream miRNA targets or functional assays were reported.
Confidence score:

0.1768
Other information
Title:

Differential CircRNA Expression Signatures May Serve as Potential Novel Biomarkers in Prostate Cancer.

Journal: Frontiers in cell and developmental biology
Published: 2021
PubMed ID: 33718350
Study type:

bioinformatics study
Data availability: The raw data supporting the conclusions of this article will be made available by the authors, without undue reservation.; https://www.frontiersin.org/articles/10.3389/fcell.2021.605686/full#supplementary-material
Code availability: -