circRNA basic information
circBase ID: -
Name: hsa_circ_FANCB
Synonym: circFANCB
Host Gene: FANCB
Genomic location(hg19): chrX:14861782-14883702:.
Genomic location(hg38): chrX:14843660-14865580:.
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0004975
MONDO name: Alzheimer disease
Disease details: Alzheimer's disease / AD
Disease DO ID:
 10652
Disease MeSH ID:
 D000544
Disease NCIt ID:
 C2866
Disease ICD11 ID:
 1611724421
Disease OMIM ID:
 -
Species: Human
Species details: Homo sapiens
Tissue specimen:

dorsolateral prefrontal cortex
Cell lines:

-
In vivo animal model:

-
circRNA-disease information
Expression pattern:
UP
Associated gene: -
Associated microRNA: -
Biological function: unknown
Molecular mechanism: -
Biological pathway or process:

not specified
Detected method:
S
Validation methods:

RNA-seq; Bioinformatics Analysis
Clinical significance:

-
Description:

circFANCB is uniquely expressed/upregulated in AD dorsolateral prefrontal cortex versus controls and was included among the top ten upregulated circRNAs. It was computationally predicted to contain miRNA-binding sites, but no specific miRNA/mRNA axis was established for circFANCB.
Confidence score:

0.1768
Other information
Title:

Investigation of the Circular Transcriptome in Alzheimer's Disease Brain.

Journal: Journal of molecular neuroscience : MN
Published: 2024
PubMed ID: 38981928
Study type:

bioinformatics study
Data availability: GSE53697; 10.1007/s12031-024-02236-0
Code availability: -