circRNA basic information
circBase ID: hsa_circ_0077837
Name: hsa_circ_EPB41L2
Synonym: -
Host Gene: EPB41L2
Genomic location(hg19): chr6:131247744-131277639:-
Genomic location(hg38): chr6:130926604-130956499:-
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0008903
MONDO name: lung cancer
Disease details: lung cancer
Disease DO ID:
 1324
Disease MeSH ID:
 -
Disease NCIt ID:
 C7377
Disease ICD11 ID:
 -
Disease OMIM ID:
 211980
Species: Human
Species details: Homo sapiens
Tissue specimen:

-
Cell lines:

A549
In vivo animal model:

-
circRNA-disease information
Expression pattern:
DN
Associated gene: -
Associated microRNA: -
Biological function: Treatment-induced circRNA that decreases with combination therapy in A549 cells.
Molecular mechanism: Not specified.
Biological pathway or process:

not specified
Detected method:
Q
Validation methods:

divergent primers PCR; RT-qPCR
Clinical significance:

-
Description:

hsa_circ_0077837 is not detected in untreated A549 cells but becomes expressed after chemotherapy exposure; its expression decreases under combined carboplatin+pemetrexed treatment, indicating a treatment-dependent response pattern.
Confidence score:

0.279
Other information
Title:

Identification of Circular RNAs as Biomarker Candidates in Lung Cancer Treatment.

Journal: Asian Pacific journal of cancer prevention : APJCP
Published: 2024
PubMed ID: 38918678
Study type:

biological research
Data availability: -
Code availability: -