circRNA basic information
circBase ID: -
Name: hsa_circ_METTL3
Synonym: circMETTL3
Host Gene: METTL3
Genomic location(hg19): -
Genomic location(hg38): -
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0009693
MONDO name: plasma cell myeloma
Disease details: Multiple myeloma / MM
Disease DO ID:
 9538
Disease MeSH ID:
 D009101
Disease NCIt ID:
 C3242
Disease ICD11 ID:
 1582389689; 526287100
Disease OMIM ID:
 254500
Species: Human
Species details: Homo sapiens
Tissue specimen:

whole BM
Cell lines:

-
In vivo animal model:

-
circRNA-disease information
Expression pattern:
UN
Associated gene: -
Associated microRNA: -
Biological function: -
Molecular mechanism: -
Biological pathway or process:

not specified
Detected method:
S
Validation methods:

RNA-seq; Survival Analysis
Clinical significance:

High expression associated with better outcome (favourable prognosis) in MM.
Description:

In MM whole bone marrow cohort, circMETTL3 was among the most significant prognostic circRNAs; higher expression was associated with better overall survival.
Confidence score:

0.2995
Other information
Title:

The Prognostic Potential of circRNAs in Multiple Myeloma: Insights From Whole Bone Marrow and Purified Plasma Cells.

Journal: Journal of cellular and molecular medicine
Published: 2024
PubMed ID: 39601341
Study type:

combined biological and clinical study
Data availability: Raw sequencing data and patient data are available upon reasonable request but will require ethical approval of the new research project and an agreement that allows data sharing between the data owner and the principal investigator/collaborators of the project and their institution(s).
Code availability: -