circRNA basic information
circBase ID: -
Name: mmu_circ_Pvt1
Synonym: circ-0005721
Host Gene: Pvt1
Genomic location(hg19): -
Genomic location(hg38): -
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0043458
MONDO name: radiation injury
Disease details: ionizing radiation exposure
Disease DO ID:
 -
Disease MeSH ID:
 D011832
Disease NCIt ID:
 -
Disease ICD11 ID:
 -
Disease OMIM ID:
 -
Species: Mouse
Species details: Mus musculus
Tissue specimen:

primary mouse cortical neurons
Cell lines:

-
In vivo animal model:

-
circRNA-disease information
Expression pattern:
UN
Associated gene: -
Associated microRNA: -
Biological function: increases during in vitro neuronal maturation
Molecular mechanism: -
Biological pathway or process:

other pathway/process (other)
Detected method:
Q
Validation methods:

RT-qPCR
Clinical significance:

-
Description:

circ-0005721 is a Pvt1-derived circRNA whose abundance increases during in vitro neuronal maturation in primary cortical neurons as measured by RT-qPCR. The study does not clearly report its radiation-induced change direction for this specific isoform in the provided text.
Confidence score:

0.1155
Other information
Title:

Exposure to Ionizing Radiation Triggers Prolonged Changes in Circular RNA Abundance in the Embryonic Mouse Brain and Primary Neurons.

Journal: Cells
Published: 2019
PubMed ID: 31357500
Study type:

biological research
Data availability: Table S1
Code availability: -