circRNA basic information
circBase ID: hsa_circ_0016201
Name: hsa_circ_DSTYK
Synonym: hsa_circRNA_100435
Host Gene: DSTYK
Genomic location(hg19): chr1:205156545-205156934:-
Genomic location(hg38): chr1:205187417-205187806:-
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0007254
MONDO name: breast cancer
Disease details: breast cancer / BC
Disease DO ID:
 1612
Disease MeSH ID:
 -
Disease NCIt ID:
 C9335
Disease ICD11 ID:
 1047754165
Disease OMIM ID:
 -
Species: Human
Species details: Homo sapiens
Tissue specimen:

tumorous tissue samples; non-tumoruos mammary gland tissue samples; adjacent-non-tumour
Cell lines:

-
In vivo animal model:

-
circRNA-disease information
Expression pattern:
DN
Associated gene: AHNAK, PPARG, CAV1
Associated microRNA: miR-141-5p
Biological function: may act as a sponge for miR-141-5p; highlighted circRNA that may play an important role in BLBC
Molecular mechanism: predicted miRNA sponge (ceRNA) for miR-141-5p
Biological pathway or process:

ceRNA regulation (other)
Detected method:
M
Validation methods:

Microarray; Bioinformatics Analysis
Clinical significance:

-
Description:

This study predicts that hsa_circ_0016201 (alias hsa_circRNA_100435) is down-regulated in breast cancer and may sponge miR-141-5p. It is included in a predicted circRNA-miRNA-mRNA network/modules and is suggested for further functional investigation, especially in the basal-like context.
Confidence score:

0.1768
Other information
Title:

Bioinformatics analysis of the potentially functional circRNA-miRNA-mRNA network in breast cancer.

Journal: PloS one
Published: 2024
PubMed ID: 38635539
Study type:

bioinformatics study
Data availability: GSE101124; GSE182471
Code availability: -