circRNA basic information
circBase ID: hsa_circ_0060456
Name: -
Synonym: hsa_circ_006045
Host Gene: -
Genomic location(hg19): chr20:42315491-42328684:+
Genomic location(hg38): chr20:43686851-43700044:+
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0001056
MONDO name: gastric cancer
Disease details: gastric cancer / GC
Disease DO ID:
 10534
Disease MeSH ID:
 -
Disease NCIt ID:
 C9331
Disease ICD11 ID:
 1397617262
Disease OMIM ID:
 613659
Species: Human
Species details: Homo sapiens
Tissue specimen:

-
Cell lines:

MGC-803; SGC-7901; NCI-N87; GES-1
In vivo animal model:

-
circRNA-disease information
Expression pattern:
DN
Associated gene: -
Associated microRNA: hsa-miR-647, hsa-miR-412-3p, hsa-miR-637, hsa-miR-660-3p, hsa-miR-16-5p
Biological function: May inhibit invasion and metastasis of gastric cancer cells.
Molecular mechanism: Predicted interaction with miR-16-5p.
Biological pathway or process:

invasion (inhibits); metastasis (inhibits); ceRNA regulation (other)
Detected method:
M
Validation methods:

RNase R Treatment; Microarray; Bioinformatics Analysis
Clinical significance:

-
Description:

hsa_circ_0060456 was down-regulated in gastric cancer cell lines according to circRNA microarray profiling. The study predicted that it has binding sites for miR-16-5p and proposed that it may suppress gastric cancer cell invasion and metastasis through miRNA interaction.
Confidence score:

0.329
Other information
Title:

[Differentially expressed circular RNAs in human gastric cancer cells].

Journal: Sheng li xue bao : [Acta physiologica Sinica]
Published: 2018
PubMed ID: 30112563
Study type:

combined biological and bioinformatics study
Data availability: -
Code availability: -