circRNA basic information
circBase ID: -
Name: hsa_circ_PTP4A2
Synonym: hsa_circRNA_100141
Host Gene: PTP4A2
Genomic location(hg19): -
Genomic location(hg38): -
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0004605
MONDO name: chronic ulcer of skin
Disease details: chronic diabetic extremity wounds / diabetic chronic refractory wounds / diabetes refractory wounds
Disease DO ID:
 8549
Disease MeSH ID:
 -
Disease NCIt ID:
 -
Disease ICD11 ID:
 -
Disease OMIM ID:
 -
Species: Human
Species details: Homo sapiens
Tissue specimen:

chronic diabetic wounds; adjacent normal skin tissues
Cell lines:

-
In vivo animal model:

-
circRNA-disease information
Expression pattern:
UP
Associated gene: -
Associated microRNA: hsa-miR-203a-3p
Biological function: unknown
Molecular mechanism: Predicted ceRNA/circRNA-miRNA interaction with miR-203a-3p in diabetic wound ceRNA network.
Biological pathway or process:

ceRNA regulation (other)
Detected method:
S
Validation methods:

RNA-seq; Clinical Sample Validation; Bioinformatics Analysis
Clinical significance:

-
Description:

hsa_circRNA_100141 is up-regulated in chronic diabetic wound tissue and is included in the predicted diabetic-wound ceRNA network. It is reported to have a network relationship with miR-203a-3p, suggesting a circRNA-miRNA regulatory interaction relevant to wound healing mechanisms.
Confidence score:

0.348
Other information
Title:

Screening and analysis of differentially expressed circRNAs and miRNAs in chronic diabetic extremity wounds.

Journal: Frontiers in surgery
Published: 2022
PubMed ID: 36439541
Study type:

combined biological and clinical study
Data availability: GEO GSE212167
Code availability: -