circRNA basic information
circBase ID: hsa_circ_0000479
Name: hsa_circ_EPSTI1
Synonym: circEPSTI1
Host Gene: EPSTI1
Genomic location(hg19): chr13:43528083-43544806:-
Genomic location(hg38): chr13:42953947-42970670:-
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0005550
MONDO name: infectious disease
Disease details: Herpesvirus infection
Disease DO ID:
 0050117
Disease MeSH ID:
 D003141
Disease NCIt ID:
 C26726
Disease ICD11 ID:
 -
Disease OMIM ID:
 -
Species: Human
Species details: Homo sapiens
Tissue specimen:

peripheral blood
Cell lines:

MRC-5; LEC; Akata
In vivo animal model:

-
circRNA-disease information
Expression pattern:
UP
Associated gene: -
Associated microRNA: -
Biological function: unknown
Molecular mechanism: not specified
Biological pathway or process:

not specified
Detected method:
S
Validation methods:

RNA-seq
Clinical significance:

-
Description:

circEPSTI1 (hsa_circ_0000479), derived from EPSTI1, is consistently induced by interferon treatment across tested cell models and is also responsive in PBMCs after IFN-beta. The study does not define a specific antiviral mechanism or downstream targets for circEPSTI1.
Confidence score:

0.1155
Other information
Title:

Interferon induced circRNAs escape herpesvirus host shutoff and suppress lytic infection.

Journal: EMBO reports
Published: 2024
PubMed ID: 38263330
Study type:

biological research
Data availability: SRA: SRP458394
Code availability: -