circRNA basic information
circBase ID: -
Name: hsa_circ_CCDC9
Synonym: -
Host Gene: CCDC9
Genomic location(hg19): -
Genomic location(hg38): -
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0005180
MONDO name: Parkinson disease
Disease details: Parkinson’s disease / PD
Disease DO ID:
 14330
Disease MeSH ID:
 D010300
Disease NCIt ID:
 C26845
Disease ICD11 ID:
 296066191
Disease OMIM ID:
 -
Species: Human
Species details: Homo sapiens
Tissue specimen:

whole blood
Cell lines:

-
In vivo animal model:

-
circRNA-disease information
Expression pattern:
DN
Associated gene: -
Associated microRNA: -
Biological function: -
Molecular mechanism: -
Biological pathway or process:

not specified
Detected method:
S
Validation methods:

RNA-seq; Bioinformatics Analysis
Clinical significance:

-
Description:

A circRNA derived from CCDC9 is identified as decreased in early-stage idiopathic Parkinson’s disease whole blood (significant in PPMI; similar decreasing trend in ICICLE-PD). The paper provides no direct mechanistic validation (e.g., miRNA sponge assays) for this circRNA.
Confidence score:

0.1768
Other information
Title:

Early-stage idiopathic Parkinson's disease is associated with reduced circular RNA expression.

Journal: NPJ Parkinson's disease
Published: 2024
PubMed ID: 38245550
Study type:

bioinformatics study
Data availability: PPMI (https://www.ppmi-info.org/); ICICLE-PD (https://data.ncl.ac.uk/)
Code availability: https://github.com/bj-w/PD-lin-circ-RNA-paper