circRNA basic information
circBase ID: hsa_circ_0079875
Name: -
Synonym: -
Host Gene: -
Genomic location(hg19): chr7:36450122-36450775:+
Genomic location(hg38): chr7:36410513-36411166:+
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0007256
MONDO name: hepatocellular carcinoma
Disease details: hepatocellular carcinoma / HCC
Disease DO ID:
 684, 686
Disease MeSH ID:
 D006528
Disease NCIt ID:
 C3099
Disease ICD11 ID:
 1294035808
Disease OMIM ID:
 114550
Species: Human
Species details: Homo sapiens
Tissue specimen:

tumour tissue samples; paired adjacent normal tissue samples
Cell lines:

-
In vivo animal model:

-
circRNA-disease information
Expression pattern:
DS
Associated gene: -
Associated microRNA: -
Biological function: unknown
Molecular mechanism: ceRNA network prediction (circRNA-miRNA-mRNA network constructed), but no specific validated axis reported for this circRNA.
Biological pathway or process:

ceRNA regulation (other)
Detected method:
Q
M
Validation methods:

Microarray; RT-qPCR; Clinical Sample Validation; Bioinformatics Analysis
Clinical significance:

Part of five selected circRNAs used to build ceRNA networks; overall, the identified circRNA-miRNA-mRNA axes correlate negatively with HCC prognosis (not specified per hsa_circ_0079875).
Description:

hsa_circ_0079875 was one of five statistically significant circRNAs in HCC tissues (tumor vs adjacent normal) validated by qRT-PCR and then included for downstream bioinformatic prediction to build circRNA-miRNA-mRNA ceRNA networks. No specific miRNA/mRNA axis or functional mechanism was reported for hsa_circ_0079875 in the final selected prognostic axes.
Confidence score:

0.4032
Other information
Title:

Construction of a ceRNA regulatory network to explore potential pathogenesis mechanisms involved in human hepatocellular carcinoma.

Journal: Scientific reports
Published: 2023
PubMed ID: 38086834
Study type:

combined biological and clinical study
Data availability: GSE242797
Code availability: -