circRNA basic information
circBase ID: hsa_circ_0005035
Name: hsa_circ_IGF1R
Synonym: -
Host Gene: IGF1R
Genomic location(hg19): chr15:99250790-99251336:+
Genomic location(hg38): chr15:98707561-98708107:+
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0019939
MONDO name: early-onset schizophrenia
Disease details: very early-onset schizophrenia / VEOS
Disease DO ID:
 -
Disease MeSH ID:
 -
Disease NCIt ID:
 -
Disease ICD11 ID:
 -
Disease OMIM ID:
 -
Species: Human
Species details: Homo sapiens
Tissue specimen:

plasma
Cell lines:

-
In vivo animal model:

-
circRNA-disease information
Expression pattern:
DN
Associated gene: -
Associated microRNA: has-miR-16-5p
Biological function: -
Molecular mechanism: ceRNA (circRNA-miRNA-mRNA) network (predicted)
Biological pathway or process:

ceRNA regulation (other)
Detected method:
S
Validation methods:

RNA-seq; Bioinformatics Analysis
Clinical significance:

potential diagnostic biomarkers for VEOS
Description:

hsa_circ_0005035 is down-regulated in plasma from VEOS patients and is derived from the host gene IGF1R. It is included in the predicted circRNA-miRNA regulatory network and is targeted by has-miR-16-5p.
Confidence score:

0.1768
Other information
Title:

Comprehensive analysis of circRNA expression profile and circRNA-miRNA-mRNA network susceptibility to very early-onset schizophrenia.

Journal: Schizophrenia (Heidelberg, Germany)
Published: 2023
PubMed ID: 37816766
Study type:

combined biological and clinical study
Data availability: The data that support the findings of this study are available on request from the corresponding author.
Code availability: -