circRNA basic information
circBase ID: hsa_circ_0003528
Name: hsa_circ_SEC24A
Synonym: -
Host Gene: SEC24A
Genomic location(hg19): chr5:134032815-134044578:+
Genomic location(hg38): chr5:134697125-134708888:+
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0007256
MONDO name: hepatocellular carcinoma
Disease details: hepatocellular carcinoma
Disease DO ID:
 684, 686
Disease MeSH ID:
 D006528
Disease NCIt ID:
 C3099
Disease ICD11 ID:
 1294035808
Disease OMIM ID:
 114550
Species: Human
Species details: Homo sapiens
Tissue specimen:

HCC tissues; paired non-tumor liver tissues
Cell lines:

HepG2; L02
In vivo animal model:

-
circRNA-disease information
Expression pattern:
UP
Associated gene: -
Associated microRNA: hsa-miR-1248, hsa-miR-370-3p, hsa-miR-589-5p, hsa-miR-486-3p, hsa-miR-192-5p, hsa-miR-215-5p
Biological function: -
Molecular mechanism: -
Biological pathway or process:

not specified
Detected method:
Q
M
Validation methods:

Microarray; Bioinformatics Analysis; RT-qPCR; Sanger Sequencing; Clinical Sample Validation
Clinical significance:

-
Description:

hsa_circ_0003528 was identified as up-regulated in HCC tissues (microarray datasets) and validated as up-regulated in HepG2 versus L02 by RT-qPCR with Sanger sequencing confirmation of the back-splice junction. The study provides only predicted miRNA interactions without functional validation.
Confidence score:

0.5135
Other information
Title:

Circular RNA Signature in Hepatocellular Carcinoma.

Journal: Journal of Cancer
Published: 2019
PubMed ID: 31293639
Study type:

combined biological and bioinformatics study
Data availability: GSE94508; GSE97332
Code availability: -