circRNA basic information
circBase ID: hsa_circ_0001380
Name: -
Synonym: -
Host Gene: -
Genomic location(hg19): -
Genomic location(hg38): -
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0007256
MONDO name: hepatocellular carcinoma
Disease details: Hepatocellular carcinoma / HCC
Disease DO ID:
 684, 686
Disease MeSH ID:
 D006528
Disease NCIt ID:
 C3099
Disease ICD11 ID:
 1294035808
Disease OMIM ID:
 114550
Species: Human
Species details: Homo sapiens
Tissue specimen:

blood exosomes
Cell lines:

-
In vivo animal model:

-
circRNA-disease information
Expression pattern:
DS
Associated gene: -
Associated microRNA: -
Biological function: Reported as the most significant differentially expressed exosomal circRNA between normal and HCC samples (no functional validation).
Molecular mechanism: Not experimentally characterized; identified via differential expression analysis in exosomal transcriptome.
Biological pathway or process:

not specified
Detected method:
M
Validation methods:

Microarray
Clinical significance:

Proposed as a meaningful exosomal circRNA in HCC, with potential value for future research (no direct clinical validation).
Description:

This study reported hsa circ 0001380/has-circ-0001380 as the most significant differentially expressed exosomal circRNA between normal and HCC samples in exoRBase-derived data. The work did not provide circRNA-specific mechanistic experiments or clinical validation for this circRNA.
Confidence score:

0.1155
Other information
Title:

Bioinformatics Study Revealed Significance of Exosome Transcriptome in Hepatocellular Carcinoma Diagnosis.

Journal: Frontiers in cell and developmental biology
Published: 2022
PubMed ID: 35573701
Study type:

bioinformatics study
Data availability: https://www.frontiersin.org/articles/10.3389/fcell.2022.813701/full#supplementary-material
Code availability: -