circRNA basic information
circBase ID: -
Name: hsa_circ_HIPK3
Synonym: circRNA385
Host Gene: HIPK3
Genomic location(hg19): -
Genomic location(hg38): -
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0008170
MONDO name: ovarian cancer
Disease details: ovarian cancer / OC
Disease DO ID:
 2394
Disease MeSH ID:
 D010051
Disease NCIt ID:
 C7431
Disease ICD11 ID:
 685124533
Disease OMIM ID:
 167000
Species: Human
Species details: Homo sapiens
Tissue specimen:

HGSOC tissues; ovarian benign lesions; normal ovarian tissues
Cell lines:

-
In vivo animal model:

-
circRNA-disease information
Expression pattern:
DN
Associated gene: -
Associated microRNA: -
Biological function: Potential tumor marker for HGSOC based on confirmed down-regulation in HGSOC tissues.
Molecular mechanism: Not specified for this individual circRNA.
Biological pathway or process:

not specified
Detected method:
Q
S
Validation methods:

circRNA-seq; RT-qPCR; Clinical Sample Validation
Clinical significance:

Expected to become a potential tumor marker for HGSOC.
Description:

circRNA385 was identified by circRNA high-throughput sequencing and validated by qRT-PCR as down-regulated in HGSOC tissues. The authors proposed it as a potential tumor marker, although no individual mechanism was reported.
Confidence score:

0.429
Other information
Title:

Circular RNA profiling reveals circRNA1656 as a novel biomarker in high grade serous ovarian cancer.

Journal: Bioscience trends
Published: 2019
PubMed ID: 31019161
Study type:

combined bioinformatics and clinical study
Data availability: -
Code availability: -