| Expression pattern: |
UP |
| Associated gene: |
- |
| Associated microRNA: |
- |
| Biological function: |
circulating extracellular circRNA detected in cancer patient serum; may reflect tumor release |
| Molecular mechanism: |
released into bloodstream as extracellular RNA |
| Biological pathway or process: |
not specified |
| Detected method: |
Q
|
| Validation methods: |
Back-Splice Junction PCR / divergent primers PCR; Clinical Sample Validation |
| Clinical significance: |
present in T-PLL serum but not in healthy controls |
| Description: |
circ 2 (a KDM1A-derived circLSD1 RNA) is detectable in serum from T-PLL patients but absent in healthy donor serum, indicating it can circulate as an extracellular RNA in a cancer context. The study does not define downstream molecular targets for circ 2. |
| Confidence score: |
0.3544 |