circRNA basic information
circBase ID: hsa_circ_0084188
Name: hsa_circ_SPIDR
Synonym: -
Host Gene: SPIDR
Genomic location(hg19): chr8:48192449-48206619:+
Genomic location(hg38): chr8:47279861-47294030:+
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0004958
MONDO name: oral cavity squamous cell carcinoma
Disease details: oral squamous cell carcinoma / OSCC
Disease DO ID:
 0050866
Disease MeSH ID:
 -
Disease NCIt ID:
 C4833
Disease ICD11 ID:
 -
Disease OMIM ID:
 -
Species: Human
Species details: Homo sapiens
Tissue specimen:

OSCC tissue; paired normal tissue
Cell lines:

-
In vivo animal model:

-
circRNA-disease information
Expression pattern:
UP
Associated gene: UHRF1BP1
Associated microRNA: hsa‐miR‐1200
Biological function: putative miRNA sponge to upregulate UHRF1BP1 expression
Molecular mechanism: Predicted ceRNA mechanism via binding hsa-miR-1200 and affecting UHRF1BP1
Biological pathway or process:

ceRNA regulation (other)
Detected method:
S
Validation methods:

RNA-seq; Bioinformatics Analysis
Clinical significance:

-
Description:

hsa_circ_0084188 (chr8:48192450-48206619; host gene SPIDR) is up-regulated in OSCC. It is predicted to act as a ceRNA by binding hsa-miR-1200 and thereby increasing UHRF1BP1 expression, based on network prediction rather than experimental validation.
Confidence score:

0.1768
Other information
Title:

Comprehensive analysis of circRNAs for N7-methylguanosine methylation modification in human oral squamous cell carcinoma.

Journal: FASEB bioAdvances
Published: 2023
PubMed ID: 37554544
Study type:

combined biological and clinical study
Data availability: GSE221398
Code availability: -