circRNA basic information
circBase ID: -
Name: -
Synonym: novel_circ_0016372
Host Gene: -
Genomic location(hg19): -
Genomic location(hg38): -
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0005583
MONDO name: non-human animal disease
Disease details: Toxoplasma gondii infection / toxoplasmosis
Disease DO ID:
 -
Disease MeSH ID:
 D000820
Disease NCIt ID:
 -
Disease ICD11 ID:
 -
Disease OMIM ID:
 -
Species: Other mammals
Species details: Felis catus
Tissue specimen:

small intestinal epithelia / ileal sections of the small intestine
Cell lines:

-
In vivo animal model:

other disease animal model
circRNA-disease information
Expression pattern:
DN
Associated gene: DGCR8, ENSFCAG00000001328, FAM107A, LZTS3, MED24, PLEKHG5, RPL3, WASF3, WDR45, novel_305
Associated microRNA: bta-miR-1291, dme-miR-210-3p, hsa-miR-1291, hsa-miR-7976
Biological function: unknown
Molecular mechanism: ceRNA mechanism via miRNA sponging (predicted)
Biological pathway or process:

immune regulation (other); ceRNA regulation (other)
Detected method:
S
Validation methods:

RNA-seq; Bioinformatics Analysis
Clinical significance:

-
Description:

novel_circ_0016372 is down-regulated in cat small intestinal epithelia after T. gondii infection and is included in a predicted circRNA-miRNA-mRNA ceRNA network. It is reported to be connected with bta-miR-1291 and multiple genes in the network, suggesting a potential miRNA-sponge/ceRNA regulatory role during infection.
Confidence score:

0.1768
Other information
Title:

Dynamic RNA profiles in the small intestinal epithelia of cats after Toxoplasma gondii infection.

Journal: Infectious diseases of poverty
Published: 2023
PubMed ID: 37491273
Study type:

biological research
Data availability: PRJNA658394; PRJNA658397; PRJNA658398; PRJNA658399; PRJNA658401; https://data.mendeley.com/datasets/x9xmmx7mfw/draft?a=b7ce2ac5-8bfa-4ca9-8d79-28a7145742a0
Code availability: -