circRNA basic information
circBase ID: hsa_circ_0001947
Name: hsa_circ_AFF2
Synonym: hsa_circAFF2_005
Host Gene: AFF2
Genomic location(hg19): chrX:147743428-147744289:+
Genomic location(hg38): chrX:148661907-148662768:+
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0005306
MONDO name: ankylosing spondylitis
Disease details: ankylosing spondylitis
Disease DO ID:
 7147
Disease MeSH ID:
 D013167
Disease NCIt ID:
 C84564
Disease ICD11 ID:
 -
Disease OMIM ID:
 -
Species: Human
Species details: Homo sapiens
Tissue specimen:

spinal ligament tissue / supraspinous and interspinous ligaments
Cell lines:

-
In vivo animal model:

-
circRNA-disease information
Expression pattern:
UP
Associated gene: -
Associated microRNA: -
Biological function: -
Molecular mechanism: -
Biological pathway or process:

not specified
Detected method:
S
Validation methods:

RNA-seq; Bioinformatics Analysis
Clinical significance:

-
Description:

hsa_circ_0001947 (hsa_circAFF2_005) was identified as significantly up-regulated in spinal ligament tissues from ankylosing spondylitis patients versus controls by RNA-seq. No specific downstream mechanism or functional validation for this circRNA was reported beyond differential expression and inclusion in bioinformatic analyses.
Confidence score:

0.1768
Other information
Title:

Profiling and Bioinformatics Analysis of Differentially Expressed circRNAs in Spinal Ligament Tissues of Patients with Ankylosing Spondylitis.

Journal: BioMed research international
Published: 2020
PubMed ID: 32626759
Study type:

combined biological and clinical study
Data availability: The datasets used and/or analyzed during the current study are available from the corresponding author on reasonable request.
Code availability: -