FISH combined with CD68 immunostaining showed co-expression of hsa-circ-0087352 with macrophages in AAA patient tissue. The study further reports that hsa_circ_0087352 promotes inflammatory responses in macrophages.
Hsa_circ_0087352 promotes the inflammatory response of macrophages in abdominal aortic aneurysm by adsorbing hsa-miR-149-5p.