circRNA basic information
circBase ID: -
Name: hsa_circ_CCDC7
Synonym: circCCDC719-13
Host Gene: CCDC7
 
 
 
 
 
 
Disease basic information
MONDO ID: MONDO:0008315
Mondo Name: prostate cancer
Disease details:
 prostate cancer
Disease DO ID: 10283
Disease MeSH ID: D011471
Disease NCIt ID: C7378
Disease ICD11 ID: -
Disease OMIM ID: -
Species: Homo sapiens
Sample Source: patient tissue
circRNA-disease information
Expression pattern:
DN
Cell type: macrophage
Cell type details: macrophages
Detected method:
cell sorting + RNA-seq; cell sorting + qRT-PCR
Description:

Flow-sorted macrophages from prostate cancer bone metastases showed lower circCCDC719-13 than macrophages from primary prostate cancer, supported by transcriptome sequencing and RT-qPCR validation. The study links reduced circCCDC719-13 in macrophages to TAM polarization and metastatic prostate cancer progression.
Other information
Title:

Regulation of macrophage plasticity by circCCDC7 19-13 through HSP90 inhibition suppresses prostate cancer progression and metastasis: a translational study.

Journal: International journal of surgery (London, England)
Published: 2025
PubMed ID: 40576192
Data availability: -