circRNA basic information
circBase ID: mmu_circ_0000451
Name: mmu_circ_Cdyl
Synonym: circCdyl
Host Gene: Cdyl
 
 
 
 
 
 
Disease basic information
MONDO ID: MONDO:0005350
Mondo Name: abdominal aortic aneurysm
Disease details:
 abdominal aortic aneurysm
Disease DO ID: 7693
Disease MeSH ID: D017544
Disease NCIt ID: -
Disease ICD11 ID: 1154633768
Disease OMIM ID: -
Species: Mus musculus
Sample Source: animal tissue; primary cell culture
circRNA-disease information
Expression pattern:
UP
Cell type: macrophage
Cell type details: primary macrophages
Detected method:
primary cell isolation + qRT-PCR
Description:

circCdyl is highly expressed in mouse macrophages, including primary macrophages, compared with other vascular cell types examined in the AAA study. Functional experiments indicate that circCdyl promotes M1 macrophage polarization and M1-type inflammation.
Other information
Title:

Circular RNA Cdyl promotes abdominal aortic aneurysm formation by inducing M1 macrophage polarization and M1-type inflammation.

Journal: Molecular therapy : the journal of the American Society of Gene Therapy
Published: 2022
PubMed ID: 34547461
Data availability: -