circRNA basic information
circBase ID: -
Name: mmu_circ_Hectd1
Synonym: mm9_circ_008488
Host Gene: Hectd1
 
 
 
 
 
 
Disease basic information
MONDO ID: MONDO:1060198
Mondo Name: ischemic stroke
Disease details:
 cerebral ischemic stroke
Disease DO ID: -
Disease MeSH ID: -
Disease NCIt ID: -
Disease ICD11 ID: -
Disease OMIM ID: -
Species: Mus musculus
Sample Source: primary cell culture
circRNA-disease information
Expression pattern:
UP
Cell type: astrocyte
Cell type details: primary mouse astrocytes
Detected method:
primary cell isolation + qRT-PCR
Description:

circHECTD1/circHectd1 expression is increased in primary mouse astrocytes after OGD-R treatment compared with control culture conditions. Knockdown of circHECTD1 attenuated OGD-R-induced astrocyte activation and autophagy-related changes in primary mouse astrocytes.
Other information
Title:

Novel insight into circular RNA HECTD1 in astrocyte activation via autophagy by targeting MIR142-TIPARP: implications for cerebral ischemic stroke.

Journal: Autophagy
Published: 2018
PubMed ID: 29938598
Data availability: -