circRNA basic information
circBase ID: -
Name: mmu_circ_HIPK3
Synonym: -
Host Gene: HIPK3
 
 
 
 
 
 
Disease basic information
MONDO ID: MONDO:0005203
Mondo Name: ischemia reperfusion injury
Disease details:
 myocardial ischemia/reperfusion injury
Disease DO ID: -
Disease MeSH ID: D015427
Disease NCIt ID: -
Disease ICD11 ID: -
Disease OMIM ID: -
Species: Mus musculus
Sample Source: primary cell culture
circRNA-celltype information
Expression pattern:
UP
Cell type: cardiomyocyte
Cell type details: cardiomyocytes
Detected method:
primary cell isolation + qRT-PCR
Description:

circHIPK3 is up-regulated in primary mouse cardiomyocytes after hypoxia/reoxygenation stimulation. Functional experiments in cardiomyocytes showed that circHIPK3 promotes H/R-induced apoptosis via the miR-20b-5p/ATG7 axis.
Other information
Title:

CircHIPK3 regulates the autophagy and apoptosis of hypoxia/reoxygenation-stimulated cardiomyocytes via the miR-20b-5p/ATG7 axis.

Journal: Cell death discovery
Published: 2021
PubMed ID: 33824287
Data availability: -