circRNA basic information
circBase ID: -
Name: mmu_circ_HIPK3
Synonym: circHIPK3
Host Gene: HIPK3
 
 
 
 
 
 
Disease basic information
MONDO ID: MONDO:0005045
Mondo Name: hypertrophic cardiomyopathy
Disease details:
 cardiac hypertrophy
Disease DO ID: 11984
Disease MeSH ID: D002312
Disease NCIt ID: C34449
Disease ICD11 ID: 1830681485
Disease OMIM ID: -
Species: Mus musculus
Sample Source: primary cell culture
circRNA-celltype information
Expression pattern:
UP
Cell type: cardiomyocyte
Cell type details: cardiomyocytes
Detected method:
primary cell isolation + qRT-PCR
Description:

In primary neonatal mouse cardiomyocytes, Ang II treatment induced an in vitro hypertrophy model and increased circHIPK3 expression compared with control cells. circHIPK3 knockdown reduced Ang II-induced cardiomyocyte hypertrophic phenotypes.
Other information
Title:

Silencing of circHIPK3 Inhibits Pressure Overload-Induced Cardiac Hypertrophy and Dysfunction by Sponging miR-185-3p.

Journal: Drug design, development and therapy
Published: 2020
PubMed ID: 33402817
Data availability: -