circRNA basic information
circBase ID: mmu_circ_0000375
Name: mmu_circ_HECTD1
Synonym: mm9_circ_002888
Host Gene: HECTD1
 
 
 
 
 
 
Disease basic information
MONDO ID: MONDO:0005960
Mondo Name: silicosis
Disease details:
 silicosis
Disease DO ID: 10325
Disease MeSH ID: D012829
Disease NCIt ID: C3369
Disease ICD11 ID: -
Disease OMIM ID: -
Species: Mus musculus
Sample Source: animal tissue
circRNA-disease information
Expression pattern:
DN
Cell type: macrophage
Cell type details: macrophages isolated from SiO2-treated mouse BALF
Detected method:
primary cell isolation + qRT-PCR
Description:

circHECTD1 was significantly decreased in macrophages isolated from BALF of SiO2-treated mice compared with NS-treated mice. Functional experiments in macrophages linked circHECTD1 to SiO2-induced macrophage activation and downstream fibroblast proliferation and migration.
Other information
Title:

circRNA Mediates Silica-Induced Macrophage Activation Via HECTD1/ZC3H12A-Dependent Ubiquitination.

Journal: Theranostics
Published: 2018
PubMed ID: 29290828
Data availability: -