circRNA basic information
circBase ID: -
Name: hsa_circ_HIPK3
Synonym: -
Host Gene: HIPK3
 
 
 
 
 
 
Disease basic information
MONDO ID: MONDO:0005178
Mondo Name: osteoarthritis
Disease details:
 osteoarthritis
Disease DO ID: 8398
Disease MeSH ID: D010003
Disease NCIt ID: C3293
Disease ICD11 ID: 558562409
Disease OMIM ID: -
Species: Homo sapiens
Sample Source: primary cell culture
circRNA-celltype information
Expression pattern:
UP
Cell type: chondrocyte
Cell type details: OA chondrocytes
Detected method:
primary cell isolation + qRT-PCR
Description:

CircHIPK3 was highly expressed in OA chondrocytes compared with normal chondrocytes/cells based on RT-qPCR. Functional assays in OA chondrocytes showed that CircHIPK3 affected apoptosis through the miR-124/SOX8 axis.
Other information
Title:

Low expression of CircRNA HIPK3 promotes osteoarthritis chondrocyte apoptosis by serving as a sponge of miR-124 to regulate SOX8.

Journal: European review for medical and pharmacological sciences
Published: 2020
PubMed ID: 32767319
Data availability: -