circRNA basic information
circBase ID: -
Name: mmu_circ_HIPK3
Synonym: circHIPK3
Host Gene: HIPK3
 
 
 
 
 
 
Disease basic information
MONDO ID: MONDO:0005068
Mondo Name: myocardial infarction
Disease details:
 myocardial infarction
Disease DO ID: 5844
Disease MeSH ID: D009203
Disease NCIt ID: C27996
Disease ICD11 ID: -
Disease OMIM ID: -
Species: Mus musculus
Sample Source: primary cell culture
circRNA-celltype information
Expression pattern:
UP
Cell type: cardiomyocyte
Cell type details: hypoxia-induced CMs
Detected method:
primary cell isolation + qRT-PCR
Description:

In primary mouse cardiomyocytes, hypoxia increased circHIPK3 and promoted its release in exosomes. These cardiomyocyte-derived exosomal circHIPK3 signals to cardiac endothelial cells during myocardial infarction-related angiogenesis.
Other information
Title:

Exosomal CircHIPK3 Released from Hypoxia-Induced Cardiomyocytes Regulates Cardiac Angiogenesis after Myocardial Infarction.

Journal: Oxidative medicine and cellular longevity
Published: 2020
PubMed ID: 32733638
Data availability: -