circRNA basic information
circBase ID: hsa_circ_0029589
Name: -
Synonym: circ_0029589
Host Gene: -
 
 
 
 
 
 
Disease basic information
MONDO ID: MONDO:0005542
Mondo Name: acute coronary syndrome
Disease details:
 acute coronary syndrome
Disease DO ID: -
Disease MeSH ID: D054058
Disease NCIt ID: C53652
Disease ICD11 ID: -
Disease OMIM ID: -
Species: Homo sapiens
Sample Source: primary cell culture
circRNA-disease information
Expression pattern:
DN
Cell type: macrophage
Cell type details: human PBMC-derived macrophages
Detected method:
primary cell isolation + qRT-PCR
Description:

hsa_circ_0029589 was significantly decreased in ox-LDL-stimulated PBMC-derived macrophages from ACS patients compared with CPS and SA groups. Functional experiments in macrophages indicated that circ_0029589 is involved in IRF-1-induced macrophage pyroptosis and inflammation.
Other information
Title:

IFN regulatory Factor-1 induced macrophage pyroptosis by modulating m6A modification of circ_0029589 in patients with acute coronary syndrome.

Journal: International immunopharmacology
Published: 2020
PubMed ID: 32674051
Data availability: -