circRNA basic information
circBase ID: hsa_circ_0006877
Name: hsa_circ_LDLR
Synonym: circLDLR
Host Gene: LDLR
 
 
 
 
 
 
Disease basic information
MONDO ID: MONDO:0008487
Mondo Name: polycystic ovary syndrome
Disease details:
 polycystic ovary syndrome / PCOS
Disease DO ID: 11612
Disease MeSH ID: D011085
Disease NCIt ID: C26862
Disease ICD11 ID: 1213633323
Disease OMIM ID: 184700
Species: Homo sapiens
Sample Source: patient tissue
circRNA-disease information
Expression pattern:
DN
Cell type: other
Cell type details: granulosa cells
Detected method:
primary cell isolation + qRT-PCR
Description:

circLDLR expression was significantly decreased in primary granulosa cells from PCOS patients compared with control patients, as measured by qRT-PCR.
Other information
Title:

Depletion of exosomal circLDLR in follicle fluid derepresses miR-1294 function and inhibits estradiol production via CYP19A1 in polycystic ovary syndrome.

Journal: Aging
Published: 2020
PubMed ID: 32651991
Data availability: -