circRNA basic information
circBase ID: hsa_circ_0000284
Name: hsa_circ_HIPK3
Synonym: -
Host Gene: HIPK3
 
 
 
 
 
 
Disease basic information
MONDO ID: MONDO:0004979
Mondo Name: asthma
Disease details:
 asthma
Disease DO ID: 2841
Disease MeSH ID: D001249
Disease NCIt ID: C28397
Disease ICD11 ID: 1656445230
Disease OMIM ID: -
Species: Homo sapiens
Sample Source: primary cell culture
circRNA-celltype information
Expression pattern:
UP
Cell type: smooth muscle cell
Cell type details: airway smooth muscle cells (ASMCs)
Detected method:
primary cell isolation + qRT-PCR
Description:

circHIPK3 is up-regulated in PDGF-induced primary cultured human airway smooth muscle cells. Knockdown of circHIPK3 represses ASMC proliferation and migration and increases apoptosis via the miR-326/STIM1 axis.
Other information
Title:

Circular RNA circHIPK3 modulates the proliferation of airway smooth muscle cells by miR-326/STIM1 axis.

Journal: Life sciences
Published: 2020
PubMed ID: 32450169
Data availability: -