circRNA basic information
circBase ID: mmu_circ_0001052
Name: mmu_circ_HIPK3
Synonym: circHIPK3
Host Gene: HIPK3
 
 
 
 
 
 
Disease basic information
MONDO ID: MONDO:0005203
Mondo Name: ischemia reperfusion injury
Disease details:
 ischemia reperfusion injury / IRI
Disease DO ID: -
Disease MeSH ID: D015427
Disease NCIt ID: -
Disease ICD11 ID: -
Disease OMIM ID: -
Species: Mus musculus
Sample Source: primary cell culture
circRNA-celltype information
Expression pattern:
DN
Cell type: endothelial cell
Cell type details: CMVECs
Detected method:
primary cell isolation + qRT-PCR
Description:

In primary mouse cardiac microvascular endothelial cells, circHIPK3 was reduced after H2O2-induced oxidative stress compared with control cells, and hypoxia-pretreated cardiomyocyte exosomes rescued its level.
Other information
Title:

Exosomal circHIPK3 Released from Hypoxia-Pretreated Cardiomyocytes Regulates Oxidative Damage in Cardiac Microvascular Endothelial Cells via the miR-29a/IGF-1 Pathway.

Journal: Oxidative medicine and cellular longevity
Published: 2019
PubMed ID: 31885817
Data availability: -