circRNA basic information
circBase ID: -
Name: mmu_circ_HIPK2
Synonym: circHIPK2
Host Gene: HIPK2
 
 
 
 
 
 
Disease basic information
MONDO ID: MONDO:0002050
Mondo Name: depressive disorder
Disease details:
 depression
Disease DO ID: 1596
Disease MeSH ID: D003866
Disease NCIt ID: C2982
Disease ICD11 ID: -
Disease OMIM ID: -
Species: Mus musculus
Sample Source: animal tissue
circRNA-disease information
Expression pattern:
UN
Cell type: astrocyte
Cell type details: GFAP-positive cells
Detected method:
cell-type co-localization
Description:

circHIPK2 was detected in GFAP-positive astrocytes in mouse hippocampi by in situ hybridization combined with immunostaining. The study links circHIPK2 to astrocyte dysfunction in CUS-induced depressive-like behavior.
Other information
Title:

Gut microbiota from NLRP3-deficient mice ameliorates depressive-like behaviors by regulating astrocyte dysfunction via circHIPK2.

Journal: Microbiome
Published: 2019
PubMed ID: 31439031
Data availability: -