circRNA basic information
circBase ID: -
Name: -
Synonym: circRNA_28313
Host Gene: -
 
 
 
 
 
 
Disease basic information
MONDO ID: MONDO:0005298
Mondo Name: osteoporosis
Disease details:
 osteoporosis
Disease DO ID: 11476
Disease MeSH ID: D010024
Disease NCIt ID: C3298
Disease ICD11 ID: 2113001430
Disease OMIM ID: 166710
Species: Mus musculus
Sample Source: primary cell culture
circRNA-disease information
Expression pattern:
UP
Cell type: macrophage
Cell type details: bone marrow macrophage cells
Detected method:
primary cell isolation + qRT-PCR
Description:

circRNA_28313 was up-regulated in primary mouse BMM cells after RANKL + CSF1-induced osteoclast differentiation compared with non-treated BMM cells. Knockdown experiments supported that circRNA_28313 modulates osteoclast differentiation in BMM cells.
Other information
Title:

CircRNA_28313/miR-195a/CSF1 axis modulates osteoclast differentiation to affect OVX-induced bone absorption in mice.

Journal: RNA biology
Published: 2019
PubMed ID: 31204558
Data availability: -