circRNA basic information
circBase ID: hsa_circ_0002082
Name: hsa_circ_MALAT1
Synonym: circ2082
Host Gene: MALAT1
 
 
 
 
 
 
Disease basic information
MONDO ID: MONDO:0007256
Mondo Name: hepatocellular carcinoma
Disease details:
 hepatocellular carcinoma
Disease DO ID: 684, 686
Disease MeSH ID: D006528
Disease NCIt ID: C3099
Disease ICD11 ID: 1294035808
Disease OMIM ID: 114550
Species: Homo sapiens
Sample Source: patient tissue; cell line-derived model
circRNA-disease information
Expression pattern:
UP
Cell type: cancer stem cell
Cell type details: cancer stem-like cells (CSCs)
Detected method:
primary cell isolation + qRT-PCR
Description:

circ-MALAT1 is significantly higher in HCC cancer stem-like cells than in adherent HCC cells based on quantitative RT-qPCR. The text links circ-MALAT1 to CSC self-renewal through PAX5/TP53 inhibition and JAK2/STAT3 activation.
Other information
Title:

Circular RNA MALAT1 as a potential target for antimetastatic therapy.

Journal: Non-coding RNA research
Published: 2026
PubMed ID: 41439030
Data availability: -