circRNA basic information
circBase ID: hsa_circ_0000173
Name: hsa_circ_ATP2B4
Synonym: -
Host Gene: ATP2B4
 
 
 
 
 
 
Disease basic information
MONDO ID: MONDO:0008170
Mondo Name: ovarian cancer
Disease details:
 ovarian cancer
Disease DO ID: 2394
Disease MeSH ID: D010051
Disease NCIt ID: C7431
Disease ICD11 ID: 685124533
Disease OMIM ID: 167000
Species: Homo sapiens
Sample Source: cell line-derived model
circRNA-celltype information
Expression pattern:
UP
Cell type: macrophage
Cell type details: macrophages
Detected method:
cell-type co-localization
Description:

EOC cell-derived EVs deliver circATP2B4 into macrophages, where circATP2B4 RNA abundance is increased and associated with M2 macrophage polarization.
Other information
Title:

Extracellular Vesicle-Packaged circATP2B4 Mediates M2 Macrophage Polarization via miR-532-3p/SREBF1 Axis to Promote Epithelial Ovarian Cancer Metastasis.

Journal: Cancer immunology research
Published: 2023
PubMed ID: 36512324
Data availability: -