circRNA basic information
circBase ID: -
Name: hsa_circ_CCDC7
Synonym: circCCDC719-13
Host Gene: CCDC7
 
 
 
 
 
 
Disease basic information
MONDO ID: MONDO:0008315
Mondo Name: prostate cancer
Disease details:
 prostate cancer
Disease DO ID: 10283
Disease MeSH ID: D011471
Disease NCIt ID: C7378
Disease ICD11 ID: -
Disease OMIM ID: -
Species: Homo sapiens
Sample Source: patient tissue
circRNA-disease information
Expression pattern:
DN
Cell type: macrophage
Cell type details: tumor-associated macrophages (TAMs)
Detected method:
cell sorting + qRT-PCR
Description:

circCCDC719-13 was decreased in sorted tumor-associated macrophages from prostate cancer tissues compared with macrophages from adjacent control tissues. Functional experiments in TAMs linked circCCDC719-13 overexpression to altered TAM polarization and reduced tumor-promoting effects.
Other information
Title:

Regulation of macrophage plasticity by circCCDC7 19-13 through HSP90 inhibition suppresses prostate cancer progression and metastasis: a translational study.

Journal: International journal of surgery (London, England)
Published: 2025
PubMed ID: 40576192
Data availability: -