circRNA basic information
circBase ID: -
Name: mmu_circ_HIPK3
Synonym: -
Host Gene: HIPK3
 
 
 
 
 
 
Disease basic information
MONDO ID: MONDO:0020248
Mondo Name: vitreoretinal degeneration
Disease details:
 vitreoretinal diseases
Disease DO ID: -
Disease MeSH ID: -
Disease NCIt ID: -
Disease ICD11 ID: -
Disease OMIM ID: -
Species: Mus musculus
Sample Source: primary cell culture
circRNA-celltype information
Expression pattern:
UP
Cell type: epithelial cell
Cell type details: retinal pigment epithelial (RPE) cells
Detected method:
primary cell isolation + qRT-PCR
Description:

In primary mouse retinal pigment epithelial cells, circHIPK3 was significantly up-regulated after TGF-β1-induced RPE-EMT compared with untreated control conditions. Functional perturbation showed that circHIPK3 regulates EMT and migration in RPE cells.
Other information
Title:

Circular RNA HIPK3 mediates epithelial-mesenchymal transition of retinal pigment epithelial cells by sponging multiple microRNAs.

Journal: Scientific reports
Published: 2024
PubMed ID: 39572643
Data availability: -