circRNA basic information
circBase ID: hsa_circ_0005589
Name: hsa_circ_ARCN1
Synonym: circARCN1
Host Gene: ARCN1
 
 
 
 
 
 
Disease basic information
MONDO ID: MONDO:0005010
Mondo Name: coronary artery disorder
Disease details:
 coronary artery disease
Disease DO ID: 3393
Disease MeSH ID: D003324
Disease NCIt ID: C26732
Disease ICD11 ID: 1059873720
Disease OMIM ID: -
Species: Homo sapiens
Sample Source: unclear
circRNA-disease information
Expression pattern:
UP
Cell type: monocyte
Cell type details: monocytes
Detected method:
cell sorting + qRT-PCR
Description:

After PBMC subset separation by plastic adherence, circARCN1 decreased when monocytes were removed and increased when monocytes were enriched, supporting monocyte-enriched expression. The study associates circulating circARCN1 with stable angina and acute coronary syndrome.
Other information
Title:

CircARCN1 aggravates atherosclerosis by regulating HuR-mediated USP31 mRNA in macrophages.

Journal: Cardiovascular research
Published: 2024
PubMed ID: 39028686
Data availability: -