circRNA basic information
circBase ID: -
Name: hsa_circ_VAPA
Synonym: circVAPA
Host Gene: VAPA
 
 
 
 
 
 
Disease basic information
MONDO ID: MONDO:0006502
Mondo Name: acute respiratory distress syndrome
Disease details:
acute respiratory distress syndrome
Disease DO ID: -
Disease MeSH ID: -
Disease NCIt ID: C3353
Disease ICD11 ID: 1189702844
Disease OMIM ID: -
Species: Homo sapiens
Sample Source: patient tissue
circRNA-disease information
Expression pattern:
UP
Cell type: macrophage
Cell type details: alveolar macrophages
Detected method:
primary cell isolation + qRT-PCR
Description:

circVAPA was up-regulated in alveolar macrophages isolated from BALF samples of ARDS patients compared with healthy controls. The study links this up-regulation to inflammatory activation of macrophages in ARDS.

Other information
Title:

Circular RNA circVAPA mediates alveolar macrophage activation by modulating miR-212-3p/Sirt1 axis in acute respiratory distress syndrome.

Journal: Journal of molecular histology
Published: 2024
PubMed ID: 39612054
Data availability: -