circRNA basic information
circBase ID: -
Name: mmu_circ_Homer1
Synonym: circHomer1
Host Gene: Homer1
 
 
 
 
 
 
Disease basic information
MONDO ID: MONDO:0005090
Mondo Name: schizophrenia
Disease details:
 schizophrenia
Disease DO ID: 5419
Disease MeSH ID: -
Disease NCIt ID: C3362
Disease ICD11 ID: 1683919430
Disease OMIM ID: 181500
Species: Mus musculus
Sample Source: primary cell culture
circRNA-disease information
Expression pattern:
DN
Cell type: neuron
Cell type details: mouse cortical neurons
Detected method:
primary cell isolation + qRT-PCR
Description:

In mouse cortical neurons, NMDA receptor blockade with MK801 reduced circHomer1 expression measured by qRT-PCR. This neuronal regulation is presented in the context of schizophrenia-relevant glutamatergic signaling.
Other information
Title:

Regulation of neuronal circHomer1 biogenesis by PKA/CREB/ERK-mediated pathways and effects of glutamate and dopamine receptor blockade.

Journal: Research square
Published: 2024
PubMed ID: 38260249
Data availability: -