circRNA basic information
circBase ID: -
Name: hsa_circ_HIPK3
Synonym: circHIPK3
Host Gene: HIPK3
 
 
 
 
 
 
Disease basic information
MONDO ID: MONDO:0020511
Mondo Name: precursor B-cell acute lymphoblastic leukemia
Disease details:
 KMT2A::AFF1 B-cell precursor acute lymphoblastic leukemia
Disease DO ID: 0080638
Disease MeSH ID: -
Disease NCIt ID: C8644
Disease ICD11 ID: 1099674056
Disease OMIM ID: -
Species: Homo sapiens
Sample Source: patient tissue
circRNA-disease information
Expression pattern:
UP
Cell type: tumor cell
Cell type details: leukemia cells
Detected method:
primary cell isolation + RNA-seq
Description:

circHIPK3 is up-regulated in KMT2A::AFF1 ALL leukemia cells compared with healthy CD34+ hematopoietic stem cells and B cells.
Other information
Title:

Functional relevance of circRNA aberrant expression in pediatric acute leukemia with KMT2A::AFF1 fusion.

Journal: Blood advances
Published: 2024
PubMed ID: 38029383
Data availability: GSE213990