circRNA basic information
circBase ID: -
Name: hsa_circ_HIPK3
Synonym: -
Host Gene: HIPK3
 
 
 
 
 
 
Disease basic information
MONDO ID: MONDO:0005041
Mondo Name: glaucoma
Disease details:
 early-onset preeclampsia
Disease DO ID: 1686
Disease MeSH ID: D005901
Disease NCIt ID: C26782
Disease ICD11 ID: 499924848
Disease OMIM ID: -
Species: Homo sapiens
Sample Source: primary cell culture
circRNA-celltype information
Expression pattern:
DN
Cell type: endothelial cell
Cell type details: primary human umbilical vein ECs (HUVECs)
Detected method:
primary cell isolation + qRT-PCR
Description:

In primary HUVECs used as endothelial cells, qRT-PCR showed circHIPK3 downregulation after sh-circHIPK3 treatment. circHIPK3 knockdown decreased FAO activity, endothelial cell proliferation, and tube formation in the EOPE-related angiogenesis model.
Other information
Title:

CircHIPK3/miR-124 affects angiogenesis in early-onset preeclampsia via CPT1A-mediated fatty acid oxidation.

Journal: Journal of molecular medicine (Berlin, Germany)
Published: 2024
PubMed ID: 38904677
Data availability: -