circRNA basic information
circBase ID: -
Name: hsa_circ_ZEB1.33
Synonym: circ-ZEB1.33
Host Gene: hsa-miR-200a-3p
 
 
 
Disease basic information
DO ID:
 684
DO name: hepatocellular carcinoma
Disease details: hepatocellular carcinoma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: human HCC cell lines (97H, Huh7, HepG2, SNU423, SNU475, L02)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: CDK6
Associated microRNA: hsa-miR-200a-3p
Biological function: promotes the proliferation
Molecular mechanism: sponging hsa-miR-200a-3p and upregulating CDK6.
Survival: poor
Supported No.:
 1
Description:

Proliferation promotion roles of the circ-ZEB1.33-miR-200a-3p-CDK6 regulating axis are existed and verified in human HCC, both tumor and serum circ-ZEB1.33 can serve as an indicator for the prognosis of HCC patients.
Other information
Title:

Circ-ZEB133 promotes the proliferation of human HCC by sponging miR-200a-3p and upregulating CDK6.

Journal: Cancer Cell Int
Published: 2018/8/21
PubMed ID: 30123094