circRNA basic information
circBase ID: hsa_circ_0041103
Name: hsa_circ_TCF25
Synonym: -
Host Gene: hsa-miR-103a-3p, hsa-miR-107
 
 
 
Disease basic information
DO ID:
 11054
DO name: urinary bladder cancer
Disease details: bladder cancer
Species: human
Species details: human
Sample type: tissue
Sample type details: -
circRNA-disease information
Detected method:
Q
M
Detected method confidence High
Expression pattern:
UP
Associated gene: CDK6
Associated microRNA: hsa-miR-103a-3p, hsa-miR-107
Biological function: promote proliferation and migration
Molecular mechanism: down-regulate hsa-miR-103a-3p and hsa-miR-107, increase CDK6 expression
Survival: -
Supported No.:
 1
Description:

Over-expression of circTCF25 could down-regulate miR-103a-3p and miR-107, increase CDK6 expression, and promote proliferation and migration in vitro and vivo.
Other information
Title:

Screening differential circular RNA expression profiles reveals the regulatory role of circTCF25-miR-103a-3p/miR-107-CDK6 pathway in bladder carcinoma.

Journal: Sci Rep
Published: 2016/8/4
PubMed ID: 27484176