circRNA basic information
circBase ID: hsa_circ_0000799
Name: hsa_circ_BPTF
Synonym: circ-BPTF
Host Gene: hsa-miR-31-5p
 
 
 
Disease basic information
DO ID:
 11054
DO name: urinary bladder cancer
Disease details: bladder cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: human BCa cell lines (UM-UC-3, T24)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: RAB27A
Associated microRNA: hsa-miR-31-5p
Biological function: promotes bladder cancer progression and recurrence
Molecular mechanism: attenuated the anti-oncogenic effect of hsa-miR-31-5p and consequently enhanced RAB27A expression
Survival: poor
Supported No.:
 1
Description:

our findings reveal that circ-BPTF promotes BCa progression through the miR-31-5p/RAB27A axis, suggesting that circ-BPTF may be a potential target for BCa treatment.
Other information
Title:

Circ-BPTF promotes bladder cancer progression and recurrence through the miR-31-5p/RAB27A axis.

Journal: Aging (Albany NY)
Published: 2018/8/14
PubMed ID: 30103209